Personalized therapy in pediatric nephrology: Problems and prospects

نویسندگان

چکیده

The term “personalized medicine” appeared only 20 years ago, but individual approaches to the therapy were known for more than a hundred years. genome decoding and development of pharmacogenetics in recent decades have opened up new ways medicine understanding concept medicine”. article uses example nephrological diseases (Denis–Drash syndrome, Freiser hypophosphatemic rickets, nephrotic syndrome) demonstrate importance molecular genetic examination improve effectiveness treatment and, most importantly, prevent iatrogenic side effects therapy. glucocorticoid children with syndrome is used studying certain factors that affect pharmacodynamic pharmacokinetic profile glucocorticosteroids.

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ژورنال

عنوان ژورنال: ?????????? ??????? ????????????? ? ?????????

سال: 2021

ISSN: ['2500-2228', '1027-4065']

DOI: https://doi.org/10.21508/1027-4065-2021-66-2-6-12